The frequency of carcinoma in solitary thyroid nodules and in multinodular goitres
نویسنده
چکیده
A retrospective study of all patients with goitre seen from 1988 to 1992 inclusive at the Muhimbili Medical Centre, Dar es Salaam was made to determine the frequency of malignancy in patients with solitary non-toxic thyroid nodule (STN) and in those with multinodular goitre (MNG). There were 60 cases of STN and 178 with MNG. Nodular goitre was found to be predominantly a disease of females with sex ratios of M:F;1:7 for the STN group and of M:F;1:13 in the MNG group. The final diagnosis in all cases was made by histology which found malignancy in 10% of STN and in 5% of MNG patients, a difference which was not statistically significant.
منابع مشابه
A STUDY OF 765 CASES OF CLINICALLY SOLITARY COLD THYROID NODULES FROM AN IODINEDEFICIENT AREA
We studied the clinical, radioisotopic, and pathologic characteristics and the incidence of cancer in clinically solitary cold nodules of the thyroid in an iodinedeficient area. The study included retrospective analysis of 765 patients who underwent thyroidectomy for a clinically single cold nodule in a ten-year period. We compared the pathological findings with clinical data. In pathologic...
متن کاملبررسی ده ساله 420 مورد تیروئید کتومی در بیمارستان شهید دکتر رهنمون
This is a retrospective study of 420 patients undergone thyroidectomy in Rahnemoon hospital during last 10 years. The results are as follows: Thyroid malignancies and surgical procedures were three times more common in female than male. Mean age was 38.2 years for male and 35.1 for female. For both sex 4th decade of life was the most common age of disease. 22% of patients had Positive family hi...
متن کاملIncidence of Goiter with Benign and Malignat Thyroid Nodules Following Radiotherapy of Scalp in Childhood
We examined 812 subjects with a history of radiation to the head for the treatment of scalp worm infestation in during childhood. 36% of the subjects had goiters grades IA and II3. Another 134 subjects ( 17%) were found to have thyroid nodularity, 85 of whom bad solitary cold nodules. 43 patients whith either a solitary cold nodule or a multinodular goiter with a priominent cold nodule were ope...
متن کاملIs the current use of thyroid scintigraphy rational?
One hundred and thirty-one consecutive requests for thyroid scintigraphy were analysed to assess their diagnostic contribution to the subsequent medical management of the patient. Forty one per cent of requests were to investigate the presence of a clinically detectable solitary nodule and, of these, one fifth had hot nodules. Diffuse goitres accounted for 38% of all referrals, but in only two ...
متن کاملThyroid cancers in nodular goitres in Northwestern Nigeria
RESULTS: There were 160 multinodular goitres during the study period, out of which 24 (15.0%) had histologically diagnosed cancer and one out of the thirteen patients with solitary thyroid nodule (7.6%) had carcinoma. The ages of the patients with carcinoma ranged from 16 to 65 years, with a mean age of 38.8 years. Eighteen (72%) were females, and 7(28%) were males. Six out of the 25 cases of c...
متن کامل